Colorless Liquid Methyl Propiolate C4H4O2 For Carbonyl Compound

Colorless Liquid Methyl Propiolate For Carbonyl Compound

Methyl propiolate undergoes Lewis acid catalyzed reactions with alkenes in high yield. Mono and 1,2-disubstituted alkenes give mainly cyclobutenes. 1,1-disubstituted, trisubstituted and tetrasubstituted alkenes give only one adducts. Use of ethylaluminum dichloride as catalyst allows the isolation of pure products from acid-sensttive alkenes. Functionalized alkenes containing nonbasic functional groups are suitable substrates. Alkenes containing more basic functional groups ae suitable if 2 equiv of catalyst is used.

Potential Health Effects Eye:

Causes eye irritation. Lachrymator (substance which increases the flow of tears). May cause chemical conjunctivitis and corneal damage.

Skin:

Causes skin irritation. May cause cyanosis of the extremities. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.

Inhalation:

Causes respiratory tract irritation. Vapors may cause dizziness or suffocation. Can produce delayed pulmonary edema. May cause burning sensation in the chest.

Chronic:

Prolonged or repeated skin contact may cause dermatitis. Effects may be delayed.