CAS No. 165252-70-0 Dinotefuran Powder For Organic Intermediate

CAS No. 165252-70-0 Dinotefuran Powder For Organic Intermediate

Dinotefuran is a broad-spectrum insecticide, which is proposed for food uses in/on leafy vegetables (except Brassica) (group 4), and for use in professional turf management, professional ornamental production, and in the residential indoor, pet, lawn and garden markets. Dinotefuran is a neonicotinoid in the nitroguanidine sub-class, same as another insecticide clothianidin. Available product chemistry, toxicology, ecological effects and environmental fate data supporting the proposed uses have been reviewed. The data and estimated risks to human health and the environment from its proposed uses are summarized below.

Dinotefuran acts through contact and ingestion and results in the cessation of feeding within several hours of contact and death shortly after. Dinotefuran does not inhibit cholinesterase or interfere with sodium channels. Therefore, its mode of action is different from those of organophosphate, carbamate, and pyrethroid compounds. It appears that Dinotefuran acts as an agonist of insect nicotinic acetylcholine receptors, but it is postulated that Dinotefuran affects the nicotinic acetylcholine binding in a mode that differs from other neonicotinoid insecticides. It is reported that Dinotefuran was highly active on a certain silverleaf whitefly strain which developed resistance against imidacloprid.