Etoxazole Intermediates Pharma 98% CAS No. 153233-91-1

Etoxazole Intermediates Pharma With CAS No. 153233-91-1

Etoxazole has a mammalian toxicity LD50 of 5 g/kg and an environmental persistence DT50 of 19 days.Toxicity towards fish is of potential concern.

Etoxazole was discovered in the 1980s by Yashima and was released for commercial use in 1998 in Japan. It is sold under various commercial preparations for crop application such as TetraSan 5 WDG and Zeal by Valent in the United States.

Etoxazole is a new type of oxazole special acaricide newly developed by Sumitomo Chemical. Patent number: EP0639572A1: Patent name: 2-(2,6-DIFLUOROPHENYL)4-(2-ETHOXY-4-TERT-BUTYLPHENYL)-2-OXAZOLINE: Patent application date: 1992-04-28: Patentee: ASHIMA KAGAKU KOGYO KK kills harmful mites by inhibiting the embryo formation of mite eggs and the molting process from larvae to adult mites. It has contact killing and stomach toxicity, no systemic properties, but it has strong chemicalbook penetration ability and is resistant to rainwater. scour. Studies have shown that etoxazole has a strong killing effect on the eggs and young nymphs of mites. It does not kill adult mites, but it can significantly inhibit the hatching rate of female adult mites. pest mite.

Toxicity

Acute oral LD50>5000mg/kg of etoxazole original drug in rats, acute percutaneous LD50>2000mg/kg, acute inhalation LC50>1.09mg/L; no irritation to rabbit eyes and skin; no sensitization to guinea pig skin; 90-day subchronic feeding toxicity test in rats The maximum no-effect dose: 6.12 mg/kg·d for male rats, 20.50 mg/kg·d for female rats; mutagenicity test: Ames test, mouse bone marrow cell micronucleus ChemicalChemicalbookalbook test, lactation test The results of the in vitro chromosomal aberration test of animal cells were all negative, and no mutagenicity was found; the acute oral LD50>5000mg/kg, acute percutaneous LD50>2000mg/kg, acute inhalation LC50> of etoxazole 110g/L suspension in rats 1.09mg/L; slightly irritating to rabbit eyes and non-irritating to rabbit skin; guinea pig skin sensitization test results showed no sensitization. Ethoxazole original drug and 110 g/L suspending agent are low toxicity acaricides.