Colorless Liquid Nmethylformamide 123-39-7 For Chemical Industry

Colorless Liquid N-Methylformamide For Chemical Industry

N-Methylformamide is used to prepare methyl isocyanate. It is used as an extraction solvent for aromatic hydrocarbons and acts as a ligand in coordination chemistry. It is employed as a solvent in oil refineries and in aluminum electrolytic capacitors. Further, it is used as a reagent in organic synthesis. In addition to this, it is used as an investigational anticancer drug and an intermediate in the production of some pharmaceutical compounds.

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications

N-Methylformamide is used to prepare methyl isocyanate. It is used as an extraction solvent for aromatic hydrocarbons and acts as a ligand in coordination chemistry. It is employed as a solvent in oil refineries and in aluminum electrolytic capacitors. Further, it is used as a reagent in organic synthesis. In addition to this, it is used as an investigational anticancer drug and an intermediate in the production of some pharmaceutical compounds.

N-Methylformamide may also be formed by amination of methyl formate.

Purification: may be purified by distillation.3 May also be dried over freshly ignited 0.4 nm molecular sieves and filtered before use.

Handling, Storage, and Precautions: N-methylformamide is not listed as a hazardous material.4a It is stable at room temperature. It may be slightly teratogenic and can cause liver damage if ingested or inhaled. N-Methylformamide should be stored in a tightly sealed container in a cool place. Medical studies have shown N-methylformamide to have antitumor activity. This reagent has also been shown to have severe hepatoxic effects, however, due to a causal depletion of hepatic GSH. Normal care should be taken when working with this reagent.