Pungent Odor Trifluoroethanoic Acid For Organic Chemical Raw Materials

Pungent Odor Trifluoroacetic Acid For Organic Chemical Raw Materials

Trifluoroacetic acid (TFA), discovered at the early 20th century, has been widely used in organic synthesis as a solvent, catalyst and reagent. Many chemical transformations should be done with the aid of TFA, including rearrangements, functional group deprotections, oxidations, reductions, condensations, hydroarylations and trifluoromethylations. This review covers TFA synthetic applications, giving to the organic chemistry research community an opportunity to go in depth on the many diverse uses of this strong acid, water miscible and low boiling point reagent.

Trifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water. Corrosive to skin, eyes and mucous membranes. Used to make other chemicals and as a solvent.

Trifluoroacetic acid can affect you when breathed in.

Trifluoroacetic acid is a corrosive chemical and contact can severely irritate and burn the skin and eyes with possible eye damage.

Breathing Trifluoroacetic acid can irritate the nose, throat and lung causing coughing, wheezing and/or shortness of breath.