C2HF3O2 Acid Trifluoroacetic Colorless Transparent Liquid With 99% Purity

Colorless Transparent Liquid Trifluoroacetic Acid With Purity Over 99%

Trifluoroacetic acid or TFA (Cas number: 76-05-1) is available to buy from Apollo Scientific.

It is a corrosive organofluorine compound widely used to cleave N-BOC & t-butyl ester groups in peptide synthesis and as a reagent in organic synthesis because of its properties: volatility, organic solvent solubility, and acidic strength.

It can be a solvent for NMR spectroscopy and can act as a calibrant in mass spectrometry.

Trifluoroacetic Acid is used more commonly than sulfuric acid in synthesis because it is less oxidizing.

As one of the UK’s leading chemical distributors, we have a global reach. With over 25,000 compounds as potential precursors in stock, and with more than 3,000 diverse compounds created in our UK labs, you can trust Apollo to deliver the solution you need.

We have stock locations in both the UK and USA, so please get in touch if you would like to learn more about how to buy Trifluoroacetic acid.

Trifluoroacetic acid is a highly corrosive substance. Contact of the liquid with the skin, eyes, and mucous membranes can cause severe burns, and ingestion can result in serious damage to the digestive tract. TFA vapor is highly irritating of the eyes and respiratory tract, and inhalation of high concentrations can lead to severe destruction of the upper respiratory tract and may be fatal as a result of pulmonary edema. Symptoms of overexposure to TFA vapor include a burning feeling, coughing, headache, nausea, and vomiting.

Trifluoroacetic acid has not been found to be carcinogenic or to show reproductive or developmental toxicity in humans.

Trifluoroacetic acid should be handled in the laboratory using the "basic prudent practices". In particular, trifluoroacetic acid should be stored in an acid cabinet away from other classes of compounds. Because of its high vapor pressure, fumes of trifluoroacetic acid can destroy labels on other bottles if the container is not tightly sealed.